Yamunotri is one of the Chardhams of Uttarakhand.
The other three being Gangotri, Kedarnath and Badrinath.
Such is the significance of Yamunotri that is to be visited first among the Char Dhams of Uttarakhand.
The other reason of Yamunotri being visited before the other dhams is that the Char Dham Yatra is essentially done from left to right.